Posterior polymorphous dystrophy of the cornea.
نویسندگان
چکیده
منابع مشابه
[Posterior polymorphous dystrophy and LASIK].
OBJECTIVE/METHOD A 50-year-old hyperopic woman requested information about refractive surgery. Vesicle and band lesions at Descemet's membrane and endothelium were suggestive of posterior polymorphous dystrophy (PPD). Lower than normal endothelial cell densities were detected. A corneal refractive procedure was not recommended in this case. RESULTS/CONCLUSIONS The presence of vesicles and ban...
متن کاملTranscriptomic Profiling of Posterior Polymorphous Corneal Dystrophy
Purpose To investigate the molecular basis of posterior polymorphous corneal dystrophy (PPCD) by examining the PPCD transcriptome and the effect of decreased ZEB1 expression on corneal endothelial cell (CEnC) gene expression. Methods Next-generation RNA sequencing (RNA-seq) analyses of corneal endothelium from two PPCD-affected individuals (one with PPCD3 and one of unknown genetic cause) com...
متن کاملPathology of posterior polymorphous degeneration of the cornea.
POSTERIOR polymorphous degeneration of the cornea is an uncommon, non-progressive, hereditary condition which is usually bilateral; in the majority of cases there is only minimal visual impairment (Duke-Elder and Leigh, 1965). The condition was first described by Koeppe (1916) as "keratitis bullosa interna", on account of the congenital pits on the posterior corneal surface. Koeppe (1920) repor...
متن کاملPosterior Corneal Steepening in Posterior Polymorphous Corneal Dystrophy.
PURPOSE The aim was to evaluate the anterior and posterior corneal topographic characteristics of three patients with posterior polymorphous corneal dystrophy (PPCD) using a rotating Scheimpflug camera combined with a Placido disc system (Sirius, CSO, Italy). CASE REPORTS Two children with unilateral PPCD and a 53-year-old woman with bilateral PPCD were diagnosed by the presence of vesicles a...
متن کاملEpithelialization of the corneal endothelium in posterior polymorphous dystrophy.
The unusual cell type present on the posterior corneal surface of posterior polymorphous dystrophy patients has been characterized. In addition to microvilli and desmosomes, these cells contain abundant 10 nm filaments which by immunofluorescent staining were shown to consist of keratin proteins, a marker for epithelial cells.
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 1968
ISSN: 0007-1161
DOI: 10.1136/bjo.52.3.270